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Search Results for " Insulin Receptor "

127

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP1259	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153
	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) functions as a substrate for insulin receptor tyrosine kinase. This substance effectively binds to insulin and exhibits the potential for utilization in scientif...
T8221	Insulin (human)	INSULIN,Insulin(human)	IGF-1R
	Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patient...		IGF-1R
TP1125	Insulin(cattle)	Insulin from bovine pancreas	IGF-1R
	Insulin bovine (Insulin from bovine pancreas) is a biologically derived two-chain polypeptide hormone, synthesized in vivo by pancreatic β cells. It is frequently utilized as a growth supplement in cell culture applicati...		IGF-1R
T8348	Phentolamine		Adrenergic Receptor
	Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist		Adrenergic Receptor
T8773	MID-1		Others , IGF-1R
	MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skelet...		Others , IGF-1R
T9030	SU4984		FGFR , IGF-1R , PDGFR
	SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).		FGFR , IGF-1R , PDGFR
T6003	GSK1904529A	GSK 4529	Apoptosis , Raf , VEGFR , IGF-1R , Syk
	GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .		Apoptosis , Raf , VEGFR , IGF-1R , Syk
T21761	HNMPA		IGF-1R
	HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote...		IGF-1R
T2349	BMS-754807		Trk receptor , c-Met/HGFR , IGF-1R
			Trk receptor , c-Met/HGFR , IGF-1R
T10539	BIBO3304 TFA		Neuropeptide Y Receptor
	BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).		Neuropeptide Y Receptor
T3079	GSK1838705A		IGF-1R , JNK , S6 Kinase , ALK
	GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.		IGF-1R , JNK , S6 Kinase , ALK
TQ0020	AMG 837 calcium hydrate		GPR
	AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).		GPR
T9609	GRK5-IN-2		GRK
	GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.		GRK
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
T8329	AR 231453		GPR
	AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.		GPR
T2607	MSDC 0160	CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others , IGF-1R , Mitochondrial Metabolism
	MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.		Others , IGF-1R , Mitochondrial Metabolism
T7127	DC260126		Apoptosis , GPR
	DC260126 is a small-molecule antagonist of FFA1 (GPR40)		Apoptosis , GPR
T21623	AS1269574	AS 1269574	GPR , TRP/TRPV Channel
	AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.		GPR , TRP/TRPV Channel
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T1791	Ceritinib	LDK378	Serine Protease , IGF-1R , ALK
	Ceritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM).		Serine Protease , IGF-1R , ALK
T22967	MEDICA16	MEDICA 16	GPR , Others , ATP Citrate Lyase
	Free fatty acid 1 (FFA1/GPR40) receptor agonist		GPR , Others , ATP Citrate Lyase
T6419	BMS-536924	HY-10262,BMS 536924,CS-0117	Apoptosis , FAK , MEK , IGF-1R , Src
	BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.		Apoptosis , FAK , MEK , IGF-1R , Src
T6080	NVP-AEW541	AEW541	FLT , Tyrosine Kinases , IGF-1R , Autophagy
	NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay.		FLT , Tyrosine Kinases , IGF-1R , Autophagy
T3171	GSK137647A	GSK 137647	GPR
	GSK137647A (GSK 137647) is a selective FFA4 agonist.		GPR
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T1791L	Ceritinib dihydrochloride	LDK378 dihydrochloride	IGF-1R , ALK
	Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of 200 pM), and also inhibits IGF-1R, InsR, and STK22D (IC50 values of 8, 7...		IGF-1R , ALK
T1918	NVP-TAE 226	TAE226	Apoptosis , FAK , c-Met/HGFR , PYK2 , IGF-1R
	NVP-TAE 226 (TAE226) is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.		Apoptosis , FAK , c-Met/HGFR , PYK2 , IGF-1R
T6079	NVP-ADW742	ADW742,ADW,GSK 552602A	Apoptosis , IGF-1R
	NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.		Apoptosis , IGF-1R
T2693	AG1024	Tyrphostin AG 1024,Tyrphostin,AGS 200	Apoptosis , IGF-1R
	AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).		Apoptosis , IGF-1R
T26656	ARH-049020	X334,X-334,X 334,ARH 049020
	ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.
T3984	GLP-1(7-36), amide	MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide	Glucagon Receptor
	GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-...		Glucagon Receptor
T27303	Farglitazar	GI-262570,GI-2570,GW 262570X,GI 262570,GI262570	PPAR
	Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes.		PPAR
T68405	KW-2450 free base		IGF-1R
	KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free ...		IGF-1R
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T37588L	GIP (1-30) amide, porcine acetate		IGF-1R
	GIP (1-30) amide, porcine acetate is an agonist of fully glucose-dependent insulinotropic polypeptide (GIP) receptor. GIP (1-30) amide, porcine acetate can weakly inhibit gastric acid secretion and strongly stimulate ins...		IGF-1R
T15810	LY2922470		GPR
	LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...		GPR
T34973	Tyrphostin 8	4-Hydroxybenzylidenemalononitrile	EGFR , GTPase
	Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ...		EGFR , GTPase
T6745	5-Iodotubercidin	5-ITu,NSC 113939	Adenosine Receptor
	5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.		Adenosine Receptor
T17177	TUG-424	TUG424	Others
	TUG-424 significantly enhances glucose-stimulated insulin secretion at 100 nM. TUG-424 is a potent and selective free fatty acid receptor 1 agonist (EC50: 32 nM).		Others
T69146	Suksdorfin		PPAR
	Suksdorfin has hypoglycemic effects, promotes adipocyte differentiation and enhances lipocalin production, activates peroxisome proliferator-activated receptor gamma (PPARγ), promotes insulin-dependent glucose uptake by ...		PPAR
T78097L	Mazdutide acetate（2259884-03-0 free base）	Mazdutide acetate（2259884-03-0 free base）,OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate	Glucagon Receptor
	Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, an...		Glucagon Receptor
T76810	Ganitumab	AMG 479	IGF-1R
	Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low concentration with KD value of 0.22 nM. Ganitumab can inhi...		IGF-1R
T3550	X-376	Ensartinib,X-396	c-Met/HGFR , ALK
	X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inh...		c-Met/HGFR , ALK
T15368L	Galantide acetate	Galantide acetate(138579-66-5 Free base)	Neuropeptide Y Receptor
	Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in t...		Neuropeptide Y Receptor
T22715	Demethylasterriquinone B1		Others
	insulin receptor (IR) activator		Others
T28983	TLK19781	TLK 19781,TLK-19781
	TLK19781 is an insulin receptor modulator.
T14142	AGL-2263		IGF-1R
	AGL-2263 is a blocker of insulin receptor (IR)		IGF-1R
T25123	AZ12253801	AZ 12253801,AZ-12253801
	AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.
T36584	HNMPA-(AM)3		Tyrosine Kinases
	HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 μM) and insu...		Tyrosine Kinases
TP1361	S961 TFA (1083433-49-1 free base)	S961 TFA
	S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.

Compounds

[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)

TP1259

Synonym: [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153

Target:

Insulin (human)

T8221

Synonym: INSULIN,Insulin(human)

Target: IGF-1R

Insulin(cattle)

TP1125

Synonym: Insulin from bovine pancreas

Target: Adrenergic Receptor

MID-1

T8773

Synonym:

Target: Others, IGF-1R

SU4984

T9030

Synonym:

Target: FGFR, IGF-1R, PDGFR

GSK1904529A

T6003

Synonym: GSK 4529

Target: Apoptosis, Raf, VEGFR, IGF-1R, Syk

Target: Trk receptor, c-Met/HGFR, IGF-1R

BIBO3304 TFA

T10539

Synonym:

Target: Neuropeptide Y Receptor

GSK1838705A

T3079

Synonym:

Target: IGF-1R, JNK, S6 Kinase, ALK

AMG 837 calcium hydrate

Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Target: Others, IGF-1R, Mitochondrial Metabolism

DC260126

T7127

Synonym:

Target: Apoptosis, GPR

AS1269574

T21623

Synonym: AS 1269574

Target: GPR, TRP/TRPV Channel

Target: Serine Protease, IGF-1R, ALK

MEDICA16

T22967

Synonym: MEDICA 16

Target: GPR, Others, ATP Citrate Lyase

BMS-536924

T6419

Synonym: HY-10262,BMS 536924,CS-0117

Target: Apoptosis, FAK, MEK, IGF-1R, Src

NVP-AEW541

T6080

Synonym: AEW541

Target: FLT, Tyrosine Kinases, IGF-1R, Autophagy

Target: GPR, Potassium Channel

Ceritinib dihydrochloride

T1791L

Synonym: LDK378 dihydrochloride

Target: Apoptosis, FAK, c-Met/HGFR, PYK2, IGF-1R

NVP-ADW742

T6079

Synonym: ADW742,ADW,GSK 552602A

Target: Apoptosis, IGF-1R

AG1024

T2693

Synonym: Tyrphostin AG 1024,Tyrphostin,AGS 200

Target: Apoptosis, IGF-1R

ARH-049020

T26656

Synonym: X334,X-334,X 334,ARH 049020

Target:

GLP-1(7-36), amide

T3984

Synonym: MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide

Target: Glucagon Receptor

Farglitazar

T27303

Synonym: GI-262570,GI-2570,GW 262570X,GI 262570,GI262570

Synonym: INT-131,AMG-131,CHS 131

Target: PPAR

GIP (1-30) amide, porcine acetate

Synonym: 4-Hydroxybenzylidenemalononitrile

Target: EGFR, GTPase

5-Iodotubercidin

T6745

Synonym: 5-ITu,NSC 113939

Target: Adenosine Receptor

Mazdutide acetate（2259884-03-0 free base）

T78097L

Synonym: Mazdutide acetate（2259884-03-0 free base）,OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate

Target: Glucagon Receptor

Synonym: Ensartinib,X-396

Target: c-Met/HGFR, ALK

Galantide acetate

T15368L

Synonym: Galantide acetate(138579-66-5 Free base)

Target: Neuropeptide Y Receptor

Demethylasterriquinone B1

Synonym: TLK 19781,TLK-19781

Synonym: AZ 12253801,AZ-12253801

Target: Tyrosine Kinases

S961 TFA (1083433-49-1 free base)

TP1361

Synonym: S961 TFA

Target:

カタログ番号	製品名	別名	ターゲット
T3386	Kaempferitrin	Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside	cell cycle arrest , Glucokinase , IGF-1R
	Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...		cell cycle arrest , Glucokinase , IGF-1R
T0760	Cholesterol	Cholesterin,Cholesteryl alcohol	Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
	Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us...		Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
T1286	Vincamine	Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval	GPR , Others
	Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.		GPR , Others
T2755	Rhoifolin	Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
	Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine	(4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine	PI3K
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...		PI3K
T4S0295	Apigenin 7-glucoside	Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin	Reactive Oxygen Species , HIV Protease
	1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 tr...		Reactive Oxygen Species , HIV Protease
T13803	N-Oleoyl glycine		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
	N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
TWO2727	Propane-1,2,3-triyl tripalmitate	Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate	Others , Endogenous Metabolite
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...		Others , Endogenous Metabolite
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
T68746	Chaetochromin
	Chaetochromin also known as 4548-G05 and NSC 345647, is an orally active, small-molecule, selective agonist of the insulin receptor. It has potent and long-lasting antidiabetic activity in vivo in mice.
T83915	Norbixin hydrate
	Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ...

天然物製品

Kaempferitrin

T3386

Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside

Target: cell cycle arrest, Glucokinase, IGF-1R

Cholesterol

T0760

Synonym: Cholesterin,Cholesteryl alcohol

Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR

Vincamine

T1286

Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval

Target: GPR, Others

Rhoifolin

T2755

Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

(2S,3R,4S)-4-Hydroxyisoleucine

T2P2919

Synonym: (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine

Target: PI3K

Apigenin 7-glucoside

T4S0295

Synonym: Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin

Target: Reactive Oxygen Species, HIV Protease

N-Oleoyl glycine

T13803

Synonym:

Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR

Propane-1,2,3-triyl tripalmitate

TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate

Target: Others, Endogenous Metabolite

Stearic acid

T2P2923

Synonym: Isostearic acid,Octadecanoic acid,Cetylacetic acid

Target: Phosphatase, Endogenous Metabolite

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

kuwanon G

T3S1612

Synonym: Moracenin B,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-04395	Insulin Receptor Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-01149	Insulin Receptor Protein, Human, Recombinant (short isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-05283	Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His)	Human	HEK293
	The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-06195	IGF1R/CD221 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-06905	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-04360	IGF1R/CD221 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-00395	Insulin Protein, Human, Recombinant	Human	Yeast
	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPY-01608	Decorin Protein, Human, Recombinant (His)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-01573	SIRP alpha Protein, Human, Recombinant (G75A, His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06052	SIRP alpha V2 Protein, Human, Recombinant (His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-02632	SIRP alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05841	SIRP alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06051	SIRP alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPK-00793	LTK Potein, Mouse, Recombinant (His)	Mouse	HEK293
	Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain.
TMPK-00863	LTK Potein, Human, Recombinant (His)	Human	HEK293
	Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain.
TMPK-01361	IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01355	IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01353	IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01354	IGF2R Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPJ-00577	INSL3 Protein, Human, Recombinant (His)	Human	Human Cells
	Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus...
TMPH-01385	GLP1R Protein, Human, Recombinant (His)	Human	HEK293
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-02676	GLP1R Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-03301	GLP1R Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-01384	GLP1R Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-03116	IL-4R Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production a...
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-termin...
TMPY-06864	GLP1R Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of li...
TMPH-02104	Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al...
TMPY-01141	Carboxypeptidase E Protein, Human, Recombinant (His)	Human	HEK293
	Carboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallocarboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active fo...
TMPH-01045	CEACAM1 Protein, Human, Recombinant	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPY-02194	SOCS3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, plac...
TMPY-00728	Carboxypeptidase E Protein, Human, Recombinant (hFc)	Human	HEK293
	Carboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallocarboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active fo...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPY-04319	IGFBP-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) t...
TMPY-04213	IGFBP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) t...
TMPY-02969	IGFBP-2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	IGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) t...
TMPH-01556	EIF2AK2 Protein, Human, Recombinant (His)	Human	Yeast
	IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to v...
TMPY-03251	IGFBP-3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPK-01205	MDL-1/CLEC5A Protein, Human, Recombinant (hFc)	Human	HEK293
	In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, i...
TMPK-01218	MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, i...
TMPY-03411	ENSA Protein, Human, Recombinant (His)	Human	E. coli
	Endosulfine alpha, also known as ENSA, belongs to the endosulfine family. It is a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine alpha is widely expressed with high levels in skeletal muscle ...
TMPY-05654	ENSA Protein, Human, Recombinant (His), Biotinylated	Human	E. coli
	Endosulfine alpha, also known as ENSA, belongs to the endosulfine family. It is a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine alpha is widely expressed with high levels in skeletal muscle ...
TMPJ-00190	CD38 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicoti...
TMPY-02677	Ephrin A5/EFNA5 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest kn...
TMPY-01749	Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest kn...
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